Baculovirus Expression Services

We offer a complete line of services related to the expression of recombinant proteins utilizing the baculovirus expression vector system. Services include production, purification and characterization of recombinant baculovirus clones in addition to process development and scale-up for protein expression. Culture volumes from 1 L to 100 liters are available using serum-free media formulations. Optimization of protein expression is accomplished using titration experiments to determine the optimal virus to cell infection ratio and time of harvest. Cell lysate production, supernatant concentration and protein purification services are available.

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Typical Services Provided:

  • Gene Synthesis
  • Transfection and Co-transfection
  • Clone Isolation and Screening
  • High-Titer Stocks
  • BIIC/TIPS Virus Banking
  • Time Course/MOI
  • Virus Production and Characterization
  • Bioreactor Volumes from 2-L to 100-L
  • Rapid Expression Protocols
  • High-Throughput Expression

Proteins Expressed and Purified:

  • Viral Glycoproteins
  • Membrane Proteins
  • VLPs
  • Enzymes
 

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